Human P2RY12 Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX85]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Lentivirus
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order lentivirus expressed human P2RY12.
Target Protein
P2RY12
Target Classificationp
GPCR
Target Family
Purinergic
Target Protein Species
Human
Protein Tag
Based on specific requirements (Flag, StrepII, His, etc.)
Buffer
HBSS
Titer
≧1.00E+8 TU/mL
Transfer Plasmid Backbone
pCDH or specific requirements
Size
100 uL*10 vials, 1 mL
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Target Research Area
Cardiovascular Research
Related Diseases
Bleeding Disorder; Nizon-Isidor Syndrome
Quality Control
Titer Determination Method
RT-qPCR
Sterility Testing
Negative
Mycoplasma Testing
Negative
Transfection Efficiency
Positive (if EGFP is included in the transfer plasmid)
Endotoxin Level
Based on specific requirements
Product Properties
Application
Stable cell line generation; Protein expression; Biochemical assays
Safety Notes
Since the HIV genes are expressed from packaging plasmids devoid of the packing signal, none of the HIV genes will be expressed in the transduced cells. The pseudotyped lentiviruses need to be used in a Biosafety Level 2 facility even if they are replication-incompetent.
Shipping
Dry ice
Storage
Store at -80°C and avoid repeated freeze-thaw cycles.
Target
Full Name
Purinergic receptor P2Y12
Introduction
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Alternative Names
HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc);P2Y purinoceptor 12;ADP-glucose receptor;G-protein coupled receptor SP1999;Gi-coupled ADP receptor HORK3;P2Y12 platelet ADP receptor;purinergic receptor P2RY12;purinergic receptor P2Y, G-protein coupled, 12;putative G-protein coupled receptor;P2RY12
Gene ID
UniProt ID
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