Human P2RY12 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX200]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human P2RY12.
Target Protein
P2RY12
Target Protein Species
Human
Target Classificationp
GPCR
Target Research Area
Cardiovascular Research
Related Diseases
Bleeding Disorder; Nizon-Isidor Syndrome
Target Family
Purinergic
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Purinergic receptor P2Y12
Introduction
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelet aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Mutations in this gene are implicated in bleeding disorder, platelet type 8 (BDPLT8). Alternative splicing results in multiple transcript variants of this gene.
Alternative Names
HORK3; P2Y12; ADPG-R; BDPLT8; SP1999; P2T(AC); P2Y(AC); P2Y(12)R; P2Y(ADP); P2Y(cyc);P2Y purinoceptor 12;ADP-glucose receptor;G-protein coupled receptor SP1999;Gi-coupled ADP receptor HORK3;P2Y12 platelet ADP receptor;purinergic receptor P2RY12;purinergic receptor P2Y, G-protein coupled, 12;putative G-protein coupled receptor;P2RY12
Gene ID
UniProt ID
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