Human FOLR1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX168]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human FOLR1.
Target Protein
FOLR1
Target Protein Species
Human
Target Classificationp
Others
Target Research Area
CNS Research
Related Diseases
Neurodegeneration Due To Cerebral Folate Transport Deficiency; Neural Tube Defects
Target Family
Others
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Folate receptor alpha
Introduction
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Alternative Names
FBP; FOLR; NCFTD; FRalpha; folate receptor alpha; FR-alpha; KB cells FBP; adult folate-binding protein; folate binding protein; folate receptor 1 (adult); folate receptor, adult; ovarian tumor-associated antigen MOv18
Gene ID
UniProt ID
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