FOLR1
The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.
Full Name | Folate receptor alpha |
Gene ID | Human: 2348 Mouse: 14275 Rat: 171049 Monkey: 718388 |
UniProt ID | Human: P15328 Mouse: P35846 Rat: A9UMV5 Monkey: F7BP60 |
Alternative Names | FBP; FOLR; NCFTD; FRalpha; folate receptor alpha; FR-alpha; KB cells FBP; adult folate-binding protein; folate binding protein; folate receptor 1 (adult); folate receptor, adult; ovarian tumor-associated antigen MOv18 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FOLR1 & CD47 Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: FOLR1 & CD47 Target Family: Others Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay