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WNK1

This gene encodes a member of the WNK subfamily of serine/threonine protein kinases. The encoded protein may be a key regulator of blood pressure by controlling the transport of sodium and chloride ions. Mutations in this gene have been associated with pseudohypoaldosteronism type II and hereditary sensory neuropathy type II. Alternatively spliced transcript variants encoding different isoforms have been described but the full-length nature of all of them has yet to be determined.

Full Name WNK lysine deficient protein kinase 1
Gene ID Human: 65125 Mouse: 232341 Rat: 116477 Monkey: 706493
UniProt ID Human: Q9H4A3 Mouse: P83741 Rat: Q9JIH7
Alternative Names KDP; PSK; p65; HSN2; HSAN2; PRKWNK1; PPP1R167;serine/threonine-protein kinase WNK1;erythrocyte 65 kDa protein;prostate-derived sterile 20-like kinase;protein kinase with no lysine 1;protein phosphatase 1, regulatory subunit 167;serine/threonine-protein kinase WNK1 1;serine/threonine-protein kinase WNK1 2

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HeLa Assay Types: Biological assays
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