VDR
The nuclear hormone receptor superfamily of ligand-inducible transcription factors includes the nuclear hormone receptor gene, which genes for the vitamin D3 receptor. This receptor also serves as a receptor for lithocholic acid, a secondary bile acid. Although the vitamin D3 receptor controls a number of different metabolic pathways, including those involved in immune response and cancer, its downstream targets are primarily related to mineral metabolism. Rickets of type II that are vitamin D resistant are linked to mutations in this gene.
Full Name | Vitamin D receptor |
Gene ID | Human: 7421 Mouse: 22337 Rat: 24873 Monkey: 706964 |
UniProt ID | Human: P11473 Mouse: P48281 Rat: P13053 M onkey: F7HFI3 |
Alternative Names | NR1I1; PPP1R163; vitamin D3 receptor; 1,25-dihydroxyvitamin D3 receptor; nuclear receptor subfamily 1 group I member 1; protein phosphatase 1, regulatory subunit 163; vitamin D (1,25- dihydroxyvitamin D3) receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: VDR Target Family: Vitamin D Receptor Target Protein Species: Human Host Cell Type: NSCLC; CHO-K1; HEK293