mProX™ Human VDR Stable Cell Line
[CAT#: S01YF-1123-KX115]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Nuclear Receptor
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The nuclear receptor family of transcription factors includes the vitamin D receptor. The VDR gene encodes the vitamin D receptor in humans. The majority of bodily tissues express VDR, which controls gene transcription related to intestine and renal calcium and other mineral transport. Glucocorticoids reduce the expression of VDR. VDR is expressed by numerous immune cell subtypes. Calcitriol is the most powerful natural agonist, and ercalcitriol, the vitamin D2 homologue, is likewise a powerful activator. Both the secondary bile acid lithocholic acid and other forms of vitamin D bind with a lower affinity. The receptor shares a sequence with the thyroid hormone and steroid receptors and is a member of the trans-acting transcriptional regulatory factor family. The customized VDR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Thomas
This VDR cell line is the best choice for laboratories wishing to minimise troubleshooting time and maximise data and experimental volumes.
Aug 08 2020
Verified Customer
Gary
The human VDR KO cell line, often used in our laboratories.
May 30 2022
Verified Customer
FAQ
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