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TSHR

This gene encodes a membrane protein that is a key regulator of thyroid cell metabolism. The encoded protein functions as a receptor for thyrothropin and thyrostimulin, and adenylate cyclase is responsible for its activity. Multiple forms of hyperthyroidism are caused by defects in this gene. Thyroid stimulating hormone (TSH) signaling pathway and hormone ligand-binding receptors are two of its related routes. G protein-coupled receptor activity and thyroid-stimulating hormone receptor activity are two Gene Ontology (GO) annotations associated with this gene.

Full Name Thyroid stimulating hormone receptor
Gene ID Human: 7253
Mouse: 22095
Rat: 25360
Monkey: 574251
UniProt ID Human: P16473
Mouse: P47750
Rat: P21463
Monkey: A0A2K5X226
Alternative Names LGR3; CHNG1; hTSHR-I; thyrotropin receptor; TSH receptor; seven transmembrane helix receptor; thyrotropin receptor-I, hTSHR-I; TSHR; Thyroid stimulating hormone receptor

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TSHR Target Family: Glycoprotein Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TSHR Target Family: Glycoprotein Hormone Receptors Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TSHR Target Family: Glycoprotein Hormone Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TSHR Target Family: Glycoprotein Hormone Family Target Protein Species: Human Host Cell Type: FTC-133;CHO-K1;HEK293
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