TREM2
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
| Full Name | Triggering receptor expressed on myeloid cells 2 |
| Gene ID | Human: 54209 Mouse: 83433 Rat: 301227 Monkey: 719740 |
| UniProt ID | Human: Q9NZC2 Mouse: Q99NH8 Rat: D3ZZ89 Monkey: F6W5Q0 |
| Alternative Names | TREM2; PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c; triggering receptor expressed on monocytes 2; triggering receptor expressed on myeloid cells 2a; Triggering receptor expressed on myeloid cells 2 |
Product List
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Magic™ Cyno TREM2 & DAP12 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX40]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 & DAP12 Target Family: Others Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Cyno TREM2 & DAP12 HEK293T Cell Line
[CAT#: S01YF-0123-KX114]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 & DAP12 Target Family: Others Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human TREM2 Stable Cell Line
[CAT#: S01YF-1023-PY293]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;BV-2
Magic™ Human TREM2 & DAP12 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX129]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 & DAP12 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human TREM2 & DAP12 HEK293T Cell Line
[CAT#: S01YF-0123-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 & DAP12 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Knockout TREM2 THP-1 Cell Line
[CAT#: S01YF-1222-KX924]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 Host Cell Type: THP-1
Magic™ Mouse TREM2 & DAP12 HEK293T Cell Line
[CAT#: S01YF-0123-KX121]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TREM2 & DAP12 Target Family: Others Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
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