TNK2
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
| Full Name | tyrosine kinase non receptor 2 |
| Gene ID | Human: 10188 Mouse: 51789 Rat: 303882 Monkey: 711655 |
| UniProt ID | Human: Q07912 Mouse: O54967 Rat: Q5U2X5 |
| Alternative Names | ACK; ACK1; ACK-1; p21cdc42Hs;activated CDC42 kinase 1;activated Cdc42-associated kinase 1; activated p21cdc42Hs kinase; tyrosine kinase non-receptor protein 2 |
Product List
Loading...
mProX™ Human TNK2 Stable Cell Line
[CAT#: S01YF-1123-KX142]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TNK2 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HCC1395; CHO-K1; HEK293
Can't find the products you're looking for? Optimize our parameters for better results.
Filter By Tag
Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
