TNK1
The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Full Name | tyrosine kinase non receptor 1 |
| Gene ID | Human: 8711 Mouse: 83813 Rat: 303247 Monkey: 715180 |
| UniProt ID | Human: Q13470 Mouse: Q99ML2 Rat: D3ZJI4 |
| Alternative Names | KOS1;non-receptor tyrosine-protein kinase TNK1;CD38 negative kinase 1 |
Product List
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mProX™ Human TNK1 Stable Cell Line
[CAT#: S01YF-1023-PY116]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;BxPC-3;MIA PaCa-2;PANC-1;AsPC-1;SU.86.86
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