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TLR9

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Full Name Toll like receptor 9
Gene ID Human: 54106 Mouse: 81897 Rat: 338457 Monkey: 574395
UniProt ID Human: Q9NR96 Mouse: Q9EQU3 Rat: Q6Y1S0 Monkey: B3Y667
Alternative Names TLR9; CD289; toll-like receptor 9; UNQ5798/PRO19605; Toll like receptor 9

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TLR9 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TLR9 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TLR9 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: THP-1 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TLR9 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TLR9 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MG-63;HOS
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