TLR8
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
Full Name | Toll like receptor 8 |
Gene ID | Human: 51311 Mouse: 170744 Rat: 684440 Monkey: 574292 |
UniProt ID | Human: Q9NR97 Mouse: P58682 Rat: A5H300 Monkey: B3Y660 |
Alternative Names | TLR8; CD288; toll-like receptor 8; Toll like receptor 8 |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: TLR8 Target Family: Immune Checkpoint Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HL-60;OCI-AML-3