TLR8
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
| Full Name | Toll like receptor 8 |
| Gene ID | Human: 51311 Mouse: 170744 Rat: 684440 Monkey: 574292 |
| UniProt ID | Human: Q9NR97 Mouse: P58682 Rat: A5H300 Monkey: B3Y660 |
| Alternative Names | TLR8; CD288; toll-like receptor 8; Toll like receptor 8 |
Product List
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Magic™ Human TLR8 HEK293 Cell Line
[CAT#: S01YF-0123-KX433]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR8 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR8 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX407]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR8 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR8 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX408]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR8 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human TLR8 Stable Cell Line
[CAT#: S01YF-1023-PY214]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HL-60;OCI-AML-3 Assay Types: Biological assays
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