TLR6
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor functionally interacts with toll-like receptor 2 to mediate cellular response to bacterial lipoproteins. A Ser249Pro polymorphism in the extracellular domain of the encoded protein may be associated with an increased of asthma is some populations.
| Full Name | Toll like receptor 6 |
| Gene ID | Human: 10333 Mouse: 21899 Rat: 305353 Monkey: 574342 |
| UniProt ID | Human: Q9Y2C9 Mouse: Q9EPW9 Rat: G3V695 Monkey: B3Y646 |
| Alternative Names | CD286; toll-like receptor 6 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR6 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
