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    mProX™ Human TLR6 Stable Cell Line

    [CAT#: S01YF-1023-PY212]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Immune Checkpoint Cell Lines

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    Product Information

    Target Family
    Immune Checkpoint
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    Immune Checkpoint Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Leprosy 1; Multisystem Inflammatory Syndrome In Children
    Gene ID
    Human:10333
    UniProt ID
    Human:Q9Y2C9

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Toll-like receptor 6 (TLR6) is another member of the TLR family, known to recognize microbial lipopeptides in conjunction with TLR2. This recognition is crucial for the innate immune response against various pathogens, including bacteria and fungi. Polymorphisms in the TLR6 gene have been studied in various populations, revealing potential associations with susceptibility to certain infections. For instance, research has shown that Chinese Cantonese populations display distinct TLR6 polymorphisms, suggesting ethnic diversity in pathogen susceptibility. Furthermore, TLR6 has been implicated in the inflammatory response associated with certain tumors, providing a potential avenue for therapeutic interventions in cancer.

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    FAQ

    chat Casey Miller (Verified Customer)

    Does TLR6 play a role in viral infections? Nov 27 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR6, along with other TLR monomers and heterodimers, has been shown to significantly inhibit the replication of enteroviruses like EV71, suggesting its role in antiviral innate responses. Nov 27 2020

    chat Casey Garcia (Verified Customer)

    Can TLR6 be targeted for cancer vaccine development? Nov 21 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR6 has been identified as a significant participant in protein-protein interactions with potential vaccine constructs, indicating its relevance in eliciting immune responses against cancers such as colorectal cancer. Nov 21 2020

    Related Products by Target
    • Magic™ Mouse TLR6 HEK293 Cell Line (CAT#: S01YF-0123-KX430)
    • mProX™ Human TLR6 Stable Cell Line (CAT#: S01YF-1023-PY212)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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