TLR5
This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.
| Full Name | Toll like receptor 5 |
| Gene ID | Human: 7100 Mouse: 53791 Rat: 289337 Monkey: 574328 |
| UniProt ID | Human: O60602 Mouse: Q9JLF7 Rat: C0LP03 Monkey: F7G9P6 |
| Alternative Names | TLR5; SLE1; TIL3; SLEB1; MELIOS; toll-like receptor 5; systemic lupus erythematosus susceptibility 1; toll/interleukin-1 receptor-like protein 3; Toll like receptor 5 |
Product List
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Magic™ Human TLR5 & CD14 HEK293 Cell Line
[CAT#: S01YF-0123-KX429]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR5 & CD14 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR5 HEK293 Cell Line
[CAT#: S01YF-0123-KX427]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR5 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR5 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX403]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR5 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR5 HEK293 Cell Line
[CAT#: S01YF-0123-KX428]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR5 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR5 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX404]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR5 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human TLR5 Stable Cell Line
[CAT#: S01YF-1023-PY211]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;4T1 Assay Types: Biological assays
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