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    mProX™ Human TLR5 Stable Cell Line

    [CAT#: S01YF-1023-PY211]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Immune Checkpoint Cell Lines

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    Host Cell Type:
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    Product Information

    Target Family
    Immune Checkpoint
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;4T1
    Target Classification
    Immune Checkpoint Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Legionnaire Disease; Melioidosis
    Gene ID
    Human:7100
    UniProt ID
    Human:O60602

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Toll-like receptor 5 (TLR5) is a member of the TLR family, which plays a critical role in innate immunity by recognizing specific molecular patterns associated with pathogens. TLR5 specifically recognizes bacterial flagellin, a component of the flagella in motile bacteria. Activation of TLR5 can lead to the induction of pro-inflammatory cytokines and the development of adaptive immune responses. Recent studies have highlighted the role of TLR5 in regulating gut microbiota and its potential therapeutic implications in conditions like inflammatory bowel disease and bacterial infections. Moreover, TLR5 signaling has been linked to bacterial translocation after traumatic hemorrhagic shock, suggesting potential therapeutic interventions targeting this pathway.

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human TLR5 Stable Cell Line (S01YF-1023-PY211). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Cameron Williams (Verified Customer)

    How does TLR5 function in the immune response to bacterial infections? Jul 31 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR5 recognizes bacterial flagellin, activating immune responses that can be crucial in defending against infections and potentially useful in developing new therapeutic strategies. Jul 31 2022

    chat Alex Garcia (Verified Customer)

    Can TLR5 be targeted for treating inflammatory diseases? Nov 11 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR5 plays a role in modulating inflammation, such as in conditions like Crohn's disease, and targeting its signaling pathway could offer new approaches for treating these diseases. Nov 11 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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