TLR2
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
| Full Name | Toll like receptor 2 |
| Gene ID | Human: 7097 Mouse: 24088 Rat: 310553 Monkey: 574290 |
| UniProt ID | Human: O60603 Mouse: Q9QUN7 Rat: E9PTD9 Monkey: B3Y618 |
| Alternative Names | TLR2; TIL4; CD282; toll-like receptor 2; toll/interleukin-1 receptor-like protein 4; Toll like receptor 2 |
Product List
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Magic™ Human TLR2 & TLR1 HEK293 Cell Line
[CAT#: S01YF-0123-KX416]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 & TLR1 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 & TLR1 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX395]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 & TLR1 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 & TLR6 HEK293 Cell Line
[CAT#: S01YF-0123-KX419]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 & TLR6 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 & TLR6 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX396]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 & TLR6 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 HEK293 Cell Line
[CAT#: S01YF-0123-KX417]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX394]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human TLR2 HEK293 KO-TLR1/6 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX397]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 KO-TLR1/6 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR2 & TLR6 HEK293 Cell Line
[CAT#: S01YF-0123-KX420]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 & TLR6 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR2 HEK293 Cell Line
[CAT#: S01YF-0123-KX418]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Mouse TLR2 HEK293 Cell Line with SEAP Reporter
[CAT#: S01YF-0123-KX398]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR2 Target Family: Immune Checkpoint Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human TLR2 Stable Cell Line
[CAT#: S01YF-1023-PY208]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
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