TLR1
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene.
| Full Name | Toll like receptor 1 |
| Gene ID | Human: 7096 Mouse: 21897 Rat: 305354 Monkey: 574289 |
| UniProt ID | Human: Q15399 Mouse: Q9EPQ1 Rat: E9PTL5 Monkey: F7AIC3 |
| Alternative Names | TLR1; TIL; CD281; rsc786; TIL. LPRS5; toll-like receptor 1; toll/interleukin-1 receptor-like protein; Toll like receptor 1 |
Product List
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- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TLR1 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1 Assay Types: Biological assays
