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    mProX™ Human TLR1 Stable Cell Line

    [CAT#: S01YF-1023-PY207]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Immune Checkpoint Cell Lines

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    Product Information

    Target Family
    Immune Checkpoint
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    Immune Checkpoint Cell Lines
    Target Research Area
    Infectious Research
    Related Diseases
    Leprosy 5; Rheumatoid Arthritis
    Gene ID
    Human:7096
    UniProt ID
    Human:Q15399

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Toll-like receptor 1 (TLR1) plays a pivotal role in the innate immune system, recognizing microbial pathogens and initiating inflammatory responses. Recent studies have delved into the intricate mechanisms of TLR1 signaling pathways, revealing its significance in various diseases. For instance, TLR1 has been associated with the pathogenesis of infectious diseases, especially in recognizing bacterial lipoproteins, which are vital for mounting an effective immune response. Furthermore, TLR1 polymorphisms have been linked to susceptibility to infections, emphasizing its genetic influence on immune responses. With the increasing understanding of TLR1's role, potential therapeutic interventions targeting its pathways are being explored, offering promising avenues for treating infectious and inflammatory diseases.

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    FAQ

    chat Taylor Brown (Verified Customer)

    How does TLR1 contribute to the immune response against pathogens? Jun 15 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TLR1, in combination with TLR2, plays a crucial role in initiating proinflammatory responses against pathogens like Borrelia burgdorferi, which can be involved in diseases such as Lyme arthritis. Jun 15 2023

    chat Taylor Johnson (Verified Customer)

    Can TLR1 be targeted for therapeutic interventions in diseases? May 27 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Targeting TLR1, particularly its interaction with other TLRs, has potential in developing therapies for conditions like nasopharyngeal carcinoma, as it is involved in cell proliferation and immune responses. May 27 2020

    Related Products by Target
    • mProX™ Human TLR1 Stable Cell Line (CAT#: S01YF-1023-PY207)
    • Magic™ Human TLR1 HEK293 Cell Line (CAT#: S01YF-0123-KX415)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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