THRB
This gene encodes a triiodothyronine nuclear hormone receptor protein. It has been demonstrated that this thyroid hormone receptor, one of many, mediates the physiologic actions of thyroid hormone. Despite some degree of redundancy, knockout studies in mice reveal that the various receptors may mediate various functions of thyroid hormone. Generalized thyroid hormone resistance (GTHR), a disease characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone, is known to be caused by mutations in this gene.
| Full Name | Thyroid hormone receptor beta |
| Gene ID | Human: 7068 Mouse: 21834 Rat: 24831 Monkey: 100429549 |
| UniProt ID | Human: P10828 Mouse: P37242 Rat: P18113 Monkey: F7G9C3 |
| Alternative Names | GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; TRbeta; C-ERBA-2; C-ERBA-BETA; thyroid hormone receptor beta; nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) |
Product List
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mProX™ Human THRB Stable Cell Line
[CAT#: S01YF-1123-KX112]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: THRB Target Family: Thyroid Hormone Receptor Target Protein Species: Human Host Cell Type: HepG2; CHO-K1; HEK293; RL95-2; KLE
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