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  • mProX™ Human THRB Stable Cell Line

    [CAT#: S01YF-1123-KX112]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Nuclear Receptor

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    Product Information

    Target Protein
    THRB
    Target Family
    Thyroid Hormone Receptor
    Target Protein Species
    Human
    Host Cell Type
    HepG2; CHO-K1; HEK293; RL95-2; KLE
    Target Classification
    Nuclear Receptor
    Target Research Area
    Metabolic Research
    Related Diseases
    Thyroid Hormone Resistance
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The human THRB gene encodes the nuclear receptor protein known as thyroid hormone receptor beta, or TR-beta. This gene codes for a triiodothyronine nuclear hormone receptor protein. It has been demonstrated that this particular receptor, one of numerous for thyroid hormone, mediates the hormone's biological effects. Thyroid hormone actions may be mediated by distinct receptors, despite some redundancy, according to studies on knockout mice. Generalized thyroid hormone resistance (GTHR) has been linked to mutations in this gene. For this gene, many transcript variants have been found; however, only one of these has been found to be fully expressed thus far. The customized THRB stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Carol

    The THRB cell line is of superior quality, and I am confident in its reliability. Sep 06 2020

    chat Verified Customer

    chat Sharon

    Its user-friendly design have simplified the process of THRB drug discovery in our lab. Nov 12 2022

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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