TGFBR1
When this gene's protein binds to TGF-beta, a heteromeric complex is created with type II TGF-beta receptors, which transmits the TGF-beta signal from the cell surface to the cytoplasm. A serine/threonine protein kinase is the protein that is encoded. This gene's mutations have been linked to the Loeys-Dietz aortic aneurysm syndrome (LDAS).
| Full Name | Transforming growth factor beta receptor 1 |
| Gene ID | Human: 7046 Mouse: 21812 Rat: 29591 Monkey: 714952 |
| UniProt ID | Human: P36897 Mouse: Q64729 Rat: P80204 Monkey: F7BNR8 |
| Alternative Names | TGFBR1; AAT5; ALK5; ESS1; LDS1; MSSE; SKR4; TBRI; ALK-5; LDS1A; LDS2A; TBR-i; TGFR-1; ACVRLK4; tbetaR-I; TGF-beta receptor type-1; activin A receptor type II-like kinase, 53kDa; activin A receptor type II-like protein kinase of 53kD; activin receptor-like kinase 5; mutant transforming growth factor beta receptor I; serine/threonine-protein kinase receptor R4; transforming growth factor beta receptor I; transforming growth factor-beta receptor type I; Transforming growth factor beta receptor 1 |
Product List
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Magic™ Human TGFBR1 Cell Membrane Isolation Product
[CAT#: S01YF-1022-KX645]
- Product Category:
- Membranes
- Target Protein: TGFBR1 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Based on specific requirements Host Cell Type: Based on specific requirements Application: Binding Assay
mProX™ Human TGFBR1 Stable Cell Line
[CAT#: S01YF-1123-KX137]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TGFBR1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: SK-HEP1; HepG2; Hep3B; CHO-K1; HEK293
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