mProX™ Human TGFBR1 Stable Cell Line
[CAT#: S01YF-1123-KX137]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
TGFBR1
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
SK-HEP1; HepG2; Hep3B; CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Cancer Research; Metabolic Research
Related Diseases
Multiple Self-Healing Squamous Epithelioma; Loeys-Dietz Syndrome
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
The TGFBR1 gene codes for the protein known as TGF-β receptor type 1 (transforming growth factor-beta). This receptor uses a mechanism known as signal transduction to transfer signals from the cell surface inside the cell. This kind of signaling allows the external environment to influence internal processes within the cell, such as promoting cell division and growth. TGF-β receptor type 1 traverses the cell membrane to perform signaling. TGF-β receptor type 1's extracellular domain is bound by a protein known as TGF-β, which activates the receptor and permits it to bind to other cell surface receptors. These three proteins combine to produce a complex that activates other proteins in the TGF-β pathway, a signaling pathway that leads to signal transduction. The customized TGFBR1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Jessica
I recently purchased the TGFBR1 KO cell line, and it has been a valuable tool in my laboratory work.
Oct 29 2021
Verified Customer
Shirley
The human TGFBR1 cell line design is well-optimized, and the provided documentation is comprehensive. It has saved me time and effort compared to traditional methods.
Jun 09 2021
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
