TEK
This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.
| Full Name | TEK receptor tyrosine kinase |
| Gene ID | Human: 7010 Mouse: 21687 Rat: 89804 Monkey: 707455 |
| UniProt ID | Human: Q02763 Mouse: Q02858 Rat: D3ZCD0 Monkey: G7PS68 |
| Alternative Names | TIE2; VMCM; GLC3E; TIE-2; VMCM1; CD202B;angiopoietin-1 receptor;TEK tyrosine kinase, endothelial;endothelial tyrosine kinase;tunica interna endothelial cell kinase;tyrosine kinase with Ig and EGF homology domains-2;tyrosine-protein kinase receptor TEK;tyrosine-protein kinase receptor TIE-2 |
Product List
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Magic™ Human TEK (high exogenous) HEK293T Cell Line
[CAT#: S01YF-1222-KX585]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TEK (high exogenous) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human TEK (middle exogenous) HEK293T Cell Line
[CAT#: S01YF-1222-KX586]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TEK (middle exogenous) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human TEK Stable Cell Line
[CAT#: S01YF-1023-PY114]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Caki-1;ACHN Assay Types: Biological assays
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