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    mProX™ Human TEK Stable Cell Line

    [CAT#: S01YF-1023-PY114]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
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    Product Information

    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;Caki-1;ACHN
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Cardiovascular Research
    Related Diseases
    Venous Malformations, Multiple Cutaneous And Mucosal; Glaucoma 3, Primary Congenital, E
    Gene ID
    Human:7010
    UniProt ID
    Human:Q02763

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    TEK, also known as TIE2, is a receptor tyrosine kinase that plays a vital role in angiogenesis, the process of new blood vessel formation. In scientific research, TEK has been extensively studied for its role in vascular development and homeostasis. Mutations in the TEK gene have been linked to various vascular anomalies, underscoring its significance in vascular biology. Furthermore, the TEK signaling pathway has been implicated in cancer progression, particularly in the context of tumor angiogenesis. The ability of tumors to form new blood vessels is crucial for their growth and metastasis, making TEK a potential therapeutic target in oncology. The receptor's involvement in both physiological and pathological angiogenesis highlights its importance in vascular biology and its potential as a therapeutic target.

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    FAQ

    chat Jordan Smith (Verified Customer)

    What is the role of TEK in clear cell renal cell carcinoma? Jul 04 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TEK inhibits the development of clear cell renal cell carcinoma by regulating AKT phosphorylation and promoting apoptosis. Jul 04 2020

    chat Alex Williams (Verified Customer)

    How does TEK affect breast cancer metastasis? Sep 28 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TEK, in conjunction with SIRT7, can promote adriamycin-induced metastasis in breast cancer. Sep 28 2021

    Related Products by Target
    • mProX™ Human TEK Stable Cell Line (CAT#: S01YF-1023-PY114)
    • Magic™ Human TEK (high exogenous) HEK293T Cell Line (CAT#: S01YF-1222-KX585)
    • Magic™ Human TEK (middle exogenous) HEK293T Cell Line (CAT#: S01YF-1222-KX586)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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