STK4
The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process.
| Full Name | serine/threonine kinase 4 |
| Gene ID | Human: 6789 Mouse: 58231 Rat: 311622 Monkey: 717730 |
| UniProt ID | Human: Q13043 Mouse: Q9JI11 Rat: D4A648 |
| Alternative Names | KRS2; MST1; YSK3;serine/threonine-protein kinase 4;STE20-like kinase MST1;hippo homolog;kinase responsive to stress 2;mammalian STE20-like protein kinase 1;mammalian sterile 20-like 1;serine/threonine-protein kinase Krs-2 |
Product List
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Magic™ Human MST1(STK4) Assay
[CAT#: S01YF-1222-KX391]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: MST1(STK4) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human STK4 Stable Cell Line
[CAT#: S01YF-1023-PY16]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H3347 Assay Types: Biological assays
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