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STK10

This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.

Full Name serine/threonine kinase 10
Gene ID Human: 6793 Mouse: 20868 Rat: 29398 Monkey: 702402
UniProt ID Human: O94804 Mouse: O55098 Rat: E9PTG8
Alternative Names LOK; PRO2729;serine/threonine-protein kinase 10;lymphocyte-oriented kinase

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STK10 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HeLa; CHO-K1; HEK293
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