STK10
This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.
Full Name | serine/threonine kinase 10 |
Gene ID | Human: 6793 Mouse: 20868 Rat: 29398 Monkey: 702402 |
UniProt ID | Human: O94804 Mouse: O55098 Rat: E9PTG8 |
Alternative Names | LOK; PRO2729;serine/threonine-protein kinase 10;lymphocyte-oriented kinase |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: STK10 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HeLa; CHO-K1; HEK293