STING1
This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.
| Full Name | Stimulator of interferon response cGAMP interactor 1 |
| Gene ID | Human: 340061 Mouse: 72512 Rat: 498840 Monkey: 694353 |
| UniProt ID | Human: Q86WV6 Mouse: Q3TBT3 Rat: F1M391 Monkey: H9YZQ6 |
| Alternative Names | STING1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173; Stimulator of interferon response cGAMP interactor 1 |
Product List
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Magic™ Human STING1 (R232 variant) HEK293 Cell Line with STAT6-SEAP Reporter
[CAT#: S01YF-0123-KX387]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: STING1 (R232 variant) Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Knockout STING1 THP-1 Cell Line
[CAT#: S01YF-1222-KX911]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: STING1 Host Cell Type: THP-1
mProX™ Human STING1 Stable Cell Line
[CAT#: S01YF-1023-PY301]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;PANC-1
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Note: All of our products are for Research Use Only (RUO). NOT intended for diagnostic, therapeutic or clinical use. We DO NOT offer patients any direct products or services. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
