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STING1

This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Full Name Stimulator of interferon response cGAMP interactor 1
Gene ID Human: 340061 Mouse: 72512 Rat: 498840 Monkey: 694353
UniProt ID Human: Q86WV6 Mouse: Q3TBT3 Rat: F1M391 Monkey: H9YZQ6
Alternative Names STING1; ERIS; MITA; MPYS; SAVI; NET23; STING; hMITA; hSTING; TMEM173; STING-beta; stimulator of interferon genes protein; N-terminal methionine-proline-tyrosine-serine plasma membrane tetraspanner; endoplasmic reticulum IFN stimulator; endoplasmic reticulum interferon stimulator; mitochondrial mediator of IRF3 activation; stimulator of interferon protein; transmembrane protein 173; Stimulator of interferon response cGAMP interactor 1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 (R232 isoform) Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 (R232 variant) Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 (R232H) Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 (S162A) Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 Host Cell Type: THP-1
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: STING1 Target Family: Others Target Protein Species: Mouse Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;PANC-1 Assay Types: Biological assays
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