SPHK2
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
| Full Name | sphingosine kinase 2 |
| Gene ID | Human: 56848 Mouse: 56632 Rat: 308589 Monkey: 718088 |
| UniProt ID | Human: Q9NRA0 Mouse: Q9JIA7 Rat: Q6AYB2 |
| Alternative Names | SK 2; SK-2; SPK 2; SPK-2;sphingosine kinase 2 |
Product List
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Magic™ Human SPHK2 Assay
[CAT#: S01YF-1222-KX491]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: SPHK2 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human SPHK2 Stable Cell Line
[CAT#: S01YF-1023-PY102]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;Huh-7 Assay Types: Biological assays
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