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SLC10A1

This gene encodes a protein that is a member of the family of integral membrane glycoproteins called sodium/bile acid cotransporters. These proteins are involved in the enterohepatic transport of bile acids. The ileal sodium/bile acid cotransporter, which has an apical cell localization and absorbs bile acids from the intestinal lumen, bile duct, and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, which is found in the basolateral membranes of hepatocytes, are two homologous transporters that are involved in the reabsorption of bile acids. This protein is crucial for maintaining the homeostasis of cholesterol since bile acids are the catabolic byproduct of cholesterol metabolism.

Full Name Solute carrier family 10 member 1
Gene ID Human: 6554
Mouse: 20493
Rat: 24777
Monkey: 712925
UniProt ID Human: Q14973
Mouse: O08705
Rat: P26435
Monkey: F6YRK3
Alternative Names SLC10A1; NTCP; FHCA2; sodium/bile acid cotransporter; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Na/taurocholate cotransporting polypeptide; cell growth-inhibiting gene 29 protein; growth-inhibiting protein 29; sodium/taurocholate cotransporter; sodium/taurocholate cotransporting polypeptide; solute carrier family 10 (sodium/bile acid cotransporter family), member 1; solute carrier family 10 (sodium/bile acid cotransporter), member 1; Solute carrier family 10 member 1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: SLC10A1 Target Family: SLC Transporter Target Protein Species: Human Host Cell Type: HepG2; CHO-K1; HEK293
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