SIGLEC8
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490).
| Full Name | Sialic acid binding Ig like lectin 8 |
| Gene ID | Human: 27181 Rat: 292846 |
| UniProt ID | Human: Q9NYZ4 Rat: F1M8J5 |
| Alternative Names | SIGLEC8; SAF2; SIGLEC-8; SIGLEC8L; sialic acid-binding Ig-like lectin 8; CDw329; SAF-2; sialoadhesin family member 2; Sialic acid binding Ig like lectin 8 |
Product List
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Magic™ Human SIGLEC8 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX268]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SIGLEC8 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
mProX™ Human SIGLEC8 Stable Cell Line
[CAT#: S01YF-1023-PY206]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;BV2 Assay Types: Biological assays
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