SCN1A
Action potentials in muscle cells and neurons are generated and propagated by voltage-dependent sodium channels, heteromeric complexes that control sodium exchange between intracellular and extracellular regions. Two smaller beta subunits and a big, pore-forming, glycosylated alpha subunit make up each sodium channel. This gene produces a sodium channel alpha subunit with six transmembrane areas in each of its four homologous domains. Epileptic encephalopathy and generalized epilepsy with febrile seizures are both linked to allelic variations of this gene.
| Full Name | Sodium voltage-gated channel alpha subunit 1 |
| Gene ID | Human: 6323 Mouse: 20265 Rat: 81574 Monkey: 704086 |
| UniProt ID | Human: P35498 Mouse: A2APX8 Rat: P04774 Monkey: A0A1D5QX02 |
| Alternative Names | DEE6; DRVT; FEB3; FHM3; NAC1; SCN1; SMEI; EIEE6; FEB3A; HBSCI; GEFSP2; Nav1.1; sodium channel protein type 1 subunit alpha; sodium channel protein type I subunit alpha; sodium channel protein, brain I alpha subunit; sodium channel voltage gated type 1 alpha subunit; sodium channel, voltage-gated, type I, alpha polypeptide; sodium channel, voltage-gated, type I, alpha subunit; voltage-gated sodium channel subunit alpha Nav1.1; SCN1A; Sodium voltage-gated channel alpha subunit 1 |
Product List
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Magic™ mPro Human SCN1A Cell Line
[CAT#: S01YF-1122-KX110]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SCN1A Target Family: Voltage Gated Sodium Channel Target Protein Species: Human
mProX™ Human SCN1A Stable Cell Line
[CAT#: S01YF-1123-KX1]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: SCN1A Target Family: Voltage Gated Sodium Channel Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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