S1PR2
This gene encodes a G protein-coupled receptor and a protein from the EDG family. The encoded protein functions as a sphingosine 1-phosphate receptor and is involved in transcriptional activation, cell survival, and proliferation. Congenital severe deafness has been linked to defects in this gene. Its associated pathways include Class A/1 and GPCR downstream signaling (Rhodopsin-like receptors). The GO annotations for this gene include integrin binding and G protein-coupled receptor activity.
Full Name | Sphingosine-1-phosphate receptor 2 |
Gene ID | Human: 9294 Mouse: 14739 Rat: 29415 Monkey: 712143 |
UniProt ID | Human: O95136 Mouse: P52592 Rat: P47752 Monkey: F7HPM1 |
Alternative Names | EDG5; H218; LPB2; S1P2; AGR16; EDG-5; DFNB68; Gpcr13; CTD-2369P2.2; S1P receptor 2; S1P receptor EDG5; S1P receptor Edg-5; deafness, autosomal recessive 68; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; sphingosine 1-phosphate receptor Edg-5; S1PR2; Sphingosine-1-phosphate receptor 2 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Target Protein Species: Mouse Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR2 Target Family: Lysophospholipid Family Target Protein Species: Mouse Host Cell Type: bEnd.3;CHO-K1;HEK293