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RPS6KB1

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Full Name ribosomal protein S6 kinase B1
Gene ID Human: 6198 Mouse: 72508 Rat: 83840 Monkey: 711979
UniProt ID Human: P23443 Mouse: Q8BSK8 Rat: P67999
Alternative Names S6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha;ribosomal protein S6 kinase beta-1;ribosomal protein S6 kinase I;ribosomal protein S6 kinase, 70kDa, polypeptide 1;serine/threonine kinase 14 alpha;serine/threonine-protein kinase 14A

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;AGS;SNU-601;SNU-1;HCT116;SW480;SW620
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