RIGI
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2.
| Full Name | RNA sensor RIG-I |
| Gene ID | Human: 23586 Mouse: 230073 Monkey: 704638 |
| UniProt ID | Human: O95786 Mouse: Q6Q899 Monkey: Q0PXR1 |
| Alternative Names | RIG1; DDX58; RIG-I; RLR-1; SGMRT2; antiviral innate immune response receptor RIG-I; ATP-dependent RNA helicase DDX58; DEAD (Asp-Glu-Ala-Asp) box polypeptide 58; DEAD box protein 58; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide; DExD/H-box helicase 58; RNA helicase RIG-I; probable ATP-dependent RNA helicase DDX58; retinoic acid-inducible gene 1 protein; retinoic acid-inducible gene I protein |
Product List
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Magic™ Human RIGI HEK293 Cell Line with Lucia luciferase Reporter
[CAT#: S01YF-0123-KX384]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: RIGI Target Family: Others Target Protein Species: Human Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
mProX™ Human RIGI Stable Cell Line
[CAT#: S01YF-1023-PY299]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;CT26 Assay Types: Biological assays
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