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    mProX™ Human RIGI Stable Cell Line

    [CAT#: S01YF-1023-PY299]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;CT26
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    CNS Research
    Related Diseases
    Singleton-Merten Syndrome 2; Singleton-Merten Dysplasia
    Gene ID
    Human:23586
    UniProt ID
    Human:O95786

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    RIGI (retinoic acid-inducible gene I) is a protein involved in innate immunity and the recognition of viral infections. Several studies have explored the applications of RIGI in different contexts. One study focused on ORF3c, a protein encoded by the SARS-CoV-2 virus, and its role in inhibiting innate sensing in infected cells. Another study investigated the use of lipid nanoparticle encapsulation to enhance the adjuvanticity of poly(I:C), a synthetic analogue of dsRNA that activates immune responses. Additionally, a study examined how the hepatitis C virus triggers an MDA5-mediated innate immune response by producing dsRNA without viral genome replication. Another study explored the role of ORF3c in modulating innate immunity by localizing to mitochondria and inhibiting IFN-β production. Lastly, a study investigated how the coxsackievirus A6 protein 2C antagonizes IFN-β production by depleting MDA5 and RIG-I. These studies highlight the diverse applications of RIGI in understanding viral infections and developing therapeutic strategies.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human RIGI Stable Cell Line (S01YF-1023-PY299). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Jordan Davis (Verified Customer)

    What is the role of RIGI in immune response against viral infections? Feb 24 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    RIGI plays a crucial role in the immune response against viral infections, such as avian influenza, by mediating antiviral activities and influencing gene expression. Feb 24 2020

    chat Peyton Garcia (Verified Customer)

    How does RIGI contribute to the regulation of antiviral responses? Jul 22 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    RIGI is involved in the regulation of antiviral responses, including the modulation of interferon alpha, which is key in controlling viral infections. Jul 22 2021

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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