PTK6
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
| Full Name | protein tyrosine kinase 6 |
| Gene ID | Human: 5753 Mouse: 20459 Rat: 366275 Monkey: 719598 |
| UniProt ID | Human: Q13882 Mouse: Q64434 Rat: D3ZDS3 |
| Alternative Names | BRK;protein-tyrosine kinase 6;PTK6 protein tyrosine kinase 6;breast tumor kinase;protein-tyrosine kinase BRK;tyrosine-protein kinase BRK |
Product List
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Magic™ Human BRK(PTK6) Assay
[CAT#: S01YF-1122-KX1042]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: BRK(PTK6) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human PTK6 Stable Cell Line
[CAT#: S01YF-1123-KX162]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTK6 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: MCF7; CHO-K1; HEK293
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