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PTK6

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.

Full Name protein tyrosine kinase 6
Gene ID Human: 5753 Mouse: 20459 Rat: 366275 Monkey: 719598
UniProt ID Human: Q13882 Mouse: Q64434 Rat: D3ZDS3
Alternative Names BRK;protein-tyrosine kinase 6;PTK6 protein tyrosine kinase 6;breast tumor kinase;protein-tyrosine kinase BRK;tyrosine-protein kinase BRK

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTK6 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: MCF7; CHO-K1; HEK293
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