mProX™ Human PTK6 Stable Cell Line

[CAT#: S01YF-1123-KX162]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX1042	Magic™ Human BRK(PTK6) in Vitro Assay	Human		Kinase Assay

Product Information

Target Protein

PTK6

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

MCF7; CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research

Related Diseases

Ovary Serous Adenocarcinoma and Breast Cancer. Among its related pathways are Signaling by PTK6 and Regulation of activated PAK-2p34 by proteasome mediated degradation

Gene ID

5753

UniProt ID

Q13882

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The PTK6 gene in humans encodes the enzyme tyrosine-protein kinase 6. Tyrosine-protein kinase 6 is a cytoplasmic non-receptor protein kinase that is often referred to as breast tumor kinase (BRK). In epithelial tissues, it may have an intracellular signal transducer role. It has been demonstrated that the encoded protein experiences autophosphorylation. When this gene is overexpressed in mammary epithelial cells, the cells become more sensitive to epidermal growth factor, which causes a partial phenotypic transformation. While it is absent in healthy breast tissue, this gene has been found to express itself at low levels in certain breast cancers. The customized PTK6 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Linda

Its reliability and user-friendly design have simplified the process of PTK6 drug discovery in our lab. Feb 03 2023

chat Verified Customer

chat Melissa

I have used the PTK6 KO cell line extensively in my studies, and it consistently delivered outstanding performance. Aug 30 2023

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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