PTH1R
This gene encodes a protein that belongs to the second subfamily of G-protein coupled receptors. This protein functions as both a parathyroid hormone (PTH) and a hormone similar to parathyroid hormone receptor (PTHLH). G proteins that activate adenylyl cyclase and the phosphatidylinositol-calcium second messenger pathway control the activation of this receptor. Chondrodysplasias of the Jansen's metaphyseal (JMC), Blomstrand (BOCD), and enchodromatosis have been linked to defects in this receptor.
| Full Name | Parathyroid hormone 1 receptor |
| Gene ID | Human: 5745 Mouse: 19228 Rat: 56813 Monkey: 712147 |
| UniProt ID | Human: Q03431 Mouse: P41593 Rat: P25961 Monkey: A0A2K5V724 |
| Alternative Names | PFE; EKNS; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related protein receptor; seven transmembrane helix receptor; PTH1R; Parathyroid hormone 1 receptor |
Product List
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Magic™ Human FLAG tagged PTH1R HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX538]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human PTH1R (NM_000316) Chem-1 Membrane Preparation
[CAT#: S01YF-0722-KX1028]
- Product Category:
- Membranes
- Target Protein: PTH1 Target Family: Parathyroid Hormone Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human PTH1R CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX91]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid hormone receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human PTH1R (NM_000316.2) HEK293T Membrane Preparation
[CAT#: S01YF-0722-KX836]
- Product Category:
- Membranes
- Target Protein: PTH1 Target Family: Parathyroid Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
mProX™ Human PTH1R Stable Cell Line
[CAT#: S01YF-1023-PY321]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Parathyroid Hormone Family Target Protein Species: Human Host Cell Type: HEK293;CHO-K1 Assay Types: Biological assays
Magic™ Human PTH1R Cell Line with 14-3-3ε Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX134]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human PTH1R Chem-1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX819]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Human PTH1R CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-0822-KX823]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human PTH1R CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX821]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human PTH1R U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX105]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human PTH1R U2OS Cell Line, Internalization assay
[CAT#: S01YF-0822-KX822]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Internalization assay
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