PTH1R
This gene encodes a protein that belongs to the second subfamily of G-protein coupled receptors. This protein functions as both a parathyroid hormone (PTH) and a hormone similar to parathyroid hormone receptor (PTHLH). G proteins that activate adenylyl cyclase and the phosphatidylinositol-calcium second messenger pathway control the activation of this receptor. Chondrodysplasias of the Jansen's metaphyseal (JMC), Blomstrand (BOCD), and enchodromatosis have been linked to defects in this receptor.
Full Name | Parathyroid hormone 1 receptor |
Gene ID | Human: 5745 Mouse: 19228 Rat: 56813 Monkey: 712147 |
UniProt ID | Human: Q03431 Mouse: P41593 Rat: P25961 Monkey: A0A2K5V724 |
Alternative Names | PFE; EKNS; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related protein receptor; seven transmembrane helix receptor; PTH1R; Parathyroid hormone 1 receptor |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid hormone receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PTH1R Target Family: Parathyroid Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Parathyroid Hormone Family Target Protein Species: Human Host Cell Type: HEK293;CHO-K1