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PTH1R

This gene encodes a protein that belongs to the second subfamily of G-protein coupled receptors. This protein functions as both a parathyroid hormone (PTH) and a hormone similar to parathyroid hormone receptor (PTHLH). G proteins that activate adenylyl cyclase and the phosphatidylinositol-calcium second messenger pathway control the activation of this receptor. Chondrodysplasias of the Jansen's metaphyseal (JMC), Blomstrand (BOCD), and enchodromatosis have been linked to defects in this receptor.

Full Name Parathyroid hormone 1 receptor
Gene ID Human: 5745
Mouse: 19228
Rat: 56813
Monkey: 712147
UniProt ID Human: Q03431
Mouse: P41593
Rat: P25961
Monkey: A0A2K5V724
Alternative Names PFE; EKNS; PTHR; PTHR1; parathyroid hormone/parathyroid hormone-related peptide receptor; PTH/PTHr receptor; PTH/PTHrP type I receptor; PTH1 receptor; parathyroid hormone receptor 1; parathyroid hormone/parathyroid hormone-related protein receptor; seven transmembrane helix receptor; PTH1R; Parathyroid hormone 1 receptor

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTH1R Target Family: Parathyroid hormone receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTH1R Target Family: Parathyroid Hormone Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: PTH1R Target Family: Parathyroid Hormone Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Parathyroid Hormone Family Target Protein Species: Human Host Cell Type: HEK293;CHO-K1
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