PROM1
This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
Full Name | Prominin 1 |
Gene ID | Human: 8842 Mouse: 19126 Rat: 60357 Monkey: 714610 |
UniProt ID | Human: O43490 Mouse: O54990 Rat: A0JN22 Monkey: F7DVV0 |
Alternative Names | PROM1; RP41; AC133; CD133; MCDR2; STGD4; CORD12; PROML1; MSTP061; prominin-1; antigen AC133; hProminin; hematopoietic stem cell antigen; prominin-like protein 1; Prominin 1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PROM1 Target Family: Others Target Protein Species: Human Host Cell Type: CT26 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PROM1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PROM1 Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SEM
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PROM1 Target Family: Others Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay