PRKCZ

Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms.

Full Name	protein kinase C zeta
Gene ID	Human: 5590 Mouse: 18754 Rat: 29340 Monkey: 714533
UniProt ID	Human: Q05513 Mouse: Q02956 Rat: P09217
Alternative Names	PKC2; PKC-ZETA;protein kinase C zeta type;nPKC-zeta

Product List

mProX™ Human PRKCZ Stable Cell Line [CAT#: S01YF-1023-PY66]

Product Category:: Membrane Protein Stable Cell Lines

Datasheet

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