PRKCE
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior.
| Full Name | protein kinase C epsilon |
| Gene ID | Human: 5581 Mouse: 18754 Rat: 29340 Monkey: 714533 |
| UniProt ID | Human: Q02156 Mouse: P16054 Rat: P09216 Monkey: G7PM48 |
| Alternative Names | PKCE; nPKC-epsilon;protein kinase C epsilon type |
Product List
Loading...
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;NOD;GBC-SD
