PRKCA
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.
| Full Name | protein kinase C alpha |
| Gene ID | Human: 5578 Mouse: 18750 Rat: 24680 Monkey: 718412 |
| UniProt ID | Human: P17252 Mouse: P20444 Rat: P05696 |
| Alternative Names | AAG6; PKCA; PRKACA; PKCI+/-; PKCalpha; PKC-alpha;protein kinase C alpha type;PKC-A;aging-associated gene 6 |
Product List
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- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PKCα(PRKCA) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MDA-MB-231;MCF-7;4T1 Assay Types: Biological assays
