PRKAA1
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
| Full Name | protein kinase AMP-activated catalytic subunit alpha 1 |
| Gene ID | Human: 5562 Mouse: 105787 Rat: 65248 Monkey: 695558 |
| UniProt ID | Human: Q13131 Mouse: Q5EG47 Rat: P54645 |
| Alternative Names | AMPK; AMPKa1; AMPK alpha 1;5'-AMP-activated protein kinase catalytic subunit alpha-1;5'-AMP-activated protein kinase, catalytic alpha-1 chain;ACACA kinase;AMP -activate kinase alpha 1 subunit;AMP-activated protein kinase,;catalytic, alpha-1;AMPK subunit alpha-1;AMPK, alpha, 1;HMGCR kinase;acetyl-CoA carboxylase kinase;hydroxymethylglutaryl-CoA reductase kinase;protein kinase, AMP-activated, alpha 1 catalytic subunit;tau-protein kinase PRKAA1 |
Product List
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mProX™ Human PRKAA1 Stable Cell Line
[CAT#: S01YF-1123-KX150]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PRKAA1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: C-4I; HTB-35; CHO-K1; HEK293
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