PPARA
Herbicides, leukotriene antagonists, plasticizers, as well as hypolipidemic medications, are all considered peroxisome proliferators since they promote an increase in the size and quantity of peroxisomes. In both plants and animals, peroxisomes are subcellular organelles that house enzymes for respiration as well as cholesterol and lipid metabolism. Peroxisome proliferators are considered to work through particular receptors known as PPARs, which are members of the superfamily of steroid hormone receptors. PPARs influence the expression of target genes involved in immunological and inflammatory responses, cell differentiation, and cell proliferation. There are three subtypes that are related to one another: alpha, beta/delta, and gamma. Nuclear transcription factor of the subtype PPAR-alpha is encoded by this gene.
| Full Name | Peroxisome proliferator activated receptor alpha |
| Gene ID | Human: 5465 Mouse: 19013 Rat: 25747 Monkey: 613250 |
| UniProt ID | Human: Q07869 Mouse: P23204 Rat: P37230 Monkey: G7N476 |
| Alternative Names | PPAR; NR1C1; hPPAR; PPARalpha; PPAR-alpha; peroxisome proliferator-activated receptor alpha; nuclear receptor subfamily 1 group C member 1; peroxisome proliferative activated receptor, alpha |
Product List
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- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PPARalpha Target Family: Peroxisome proliferator-activated Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Protein-Protein Interaction Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PPARalpha Target Family: Peroxisome proliferator-activated Receptor Target Protein Species: Human Assay Types: Protein-Protein Interaction Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PPARalpha Target Family: Peroxisome proliferator-activated Receptor Target Protein Species: Human Assay Types: Radioligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PPARA Target Family: Peroxisome Proliferator-activated Receptor Target Protein Species: Human Host Cell Type: HepG2; Huh-7; CHO-K1; HEK293
