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PDK2

This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Full Name pyruvate dehydrogenase kinase 2
Gene ID Human: 5164 Mouse: 18604 Rat: 81530 Monkey: 704169
UniProt ID Human: Q15119 Mouse: Q9JK42 Rat: Q64536 Monkey: Q4R567
Alternative Names pyruvate dehydrogenase kinase, isozyme 2;PDH kinase 2;[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial;pyruvate dehydrogenase kinase, isoenzyme 2;pyruvate dehydrogenase, lipoamide, kinase isozyme 2, mitochondrial

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;RMG-I
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