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PBK

This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

Full Name PDZ binding kinase
Gene ID Human: 55872 Mouse: 52033 Rat: 290326 Monkey: 713242
UniProt ID Human: Q96KB5 Mouse: Q9JJ78 Rat: A1L1J7 Monkey: G7PCZ1
Alternative Names SPK; CT84; TOPK; HEL164; Nori-3;lymphokine-activated killer T-cell-originated protein kinase;MAPKK-like protein kinase;T-LAK cell-originated protein kinase;cancer/testis antigen 84;epididymis luminal protein 164;serine/threonine protein kinase;spermatogenesis-related protein kinase

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Magic™ Human PBK Assay [CAT#: S01YF-1222-KX422]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: PBK Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MDA-MB-231 Assay Types: Biological assays
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