PAK6
This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants.
| Full Name | p21 (RAC1) activated kinase 6 |
| Gene ID | Human: 56924 Mouse: 214230 Rat: 296078 Monkey: 701589 |
| UniProt ID | Human: Q9NQU5 Mouse: Q3ULB5 Rat: D3ZQ51 |
| Alternative Names | PAK5;serine/threonine-protein kinase PAK 6;p21 protein (Cdc42/Rac)-activated kinase 6;p21(CDKN1A)-activated kinase 6 |
Product List
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mProX™ Human PAK6 Stable Cell Line
[CAT#: S01YF-1023-PY45]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HeLa
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