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PAK3

The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified.

Full Name p21 (RAC1) activated kinase 3
Gene ID Human: 5063 Mouse: 18481 Rat: 29433 Monkey: 706217
UniProt ID Human: O75914 Mouse: Q61036 Rat: Q62829
Alternative Names ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; XLID30; PAK3beta; beta-PAK;serine/threonine-protein kinase PAK 3;adriamycin resistance-associated;oligophrenin-3;p21 (CDKN1A)-activated kinase 3;p21 protein (Cdc42/Rac)-activated kinase 3

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Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HepG2;Huh-7;Hep3B
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