PAK3
The protein encoded by this gene is a serine-threonine kinase and forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of a non-syndromic form of X-linked intellectual disability. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Full Name | p21 (RAC1) activated kinase 3 |
| Gene ID | Human: 5063 Mouse: 18481 Rat: 29433 Monkey: 706217 |
| UniProt ID | Human: O75914 Mouse: Q61036 Rat: Q62829 |
| Alternative Names | ARA; bPAK; MRX30; MRX47; OPHN3; PAK-3; XLID30; PAK3beta; beta-PAK;serine/threonine-protein kinase PAK 3;adriamycin resistance-associated;oligophrenin-3;p21 (CDKN1A)-activated kinase 3;p21 protein (Cdc42/Rac)-activated kinase 3 |
Product List
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Magic™ Human PAK3 Assay
[CAT#: S01YF-1222-KX417]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: PAK3 Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human PAK3 Stable Cell Line
[CAT#: S01YF-1023-PY42]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HepG2;Huh-7;Hep3B Assay Types: Biological assays
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